Deep Vein Thrombosis (DVT) Point-of-Care Ultrasound (POCUS)
Compression Ultrasonography (CUS)
The normal vein completely collapses with probe pressure.
A thrombosed vein does not compress.
Thus:
“Loss of compressibility = DVT until proven otherwise”
Types of DVT Exam
|
Exam Type |
Veins Evaluated |
Clinical Use |
|
2-point compression |
Common femoral + popliteal |
Rapid ED screening |
|
3-point compression |
Common femoral + femoral + popliteal |
Most common POCUS protocol |
|
Whole-leg ultrasound |
Entire deep venous system |
Comprehensive radiology exam |
|
Duplex ultrasound |
Compression + Doppler |
Gold standard |
|
Serial ultrasound |
Repeat exam after 5–7 days |
If initial negative but suspicion high |
Sensitivity and Specificity Proximal DVT
|
Method |
Sensitivity |
Specificity |
|
2-point CUS |
~90–95% |
~95–98% |
|
3-point CUS |
~95% |
~96–98% |
|
Whole-leg duplex |
Highest |
Highest |
Venous Anatomy Relevant to DVT POCUS
Lower Extremity Deep Venous System
Proximal veins
- Common femoral vein (CFV)
- Femoral vein (formerly superficial femoral vein)
- Deep femoral vein
- Popliteal vein
Distal calf veins
- Posterior tibial veins
- Peroneal veins
- Anterior tibial veins
- Muscular calf veins
- Soleal
- Gastrocnemius
Clinically Classification
|
Type |
Location |
Clinical Importance |
|
Proximal DVT |
Popliteal or above |
High PE risk |
|
Distal DVT |
Below popliteal |
Lower PE risk |
|
Iliofemoral DVT |
Iliac/femoral |
Severe disease |
|
Upper-extremity DVT |
Axillary/subclavian |
Central line-associated |
Ultrasound Probe Selection
|
Probe |
Frequency |
Use |
|
Linear probe |
5–15 MHz |
Standard for DVT |
|
Curvilinear |
2–5 MHz |
Obese patients |
Patient Positioning
Reverse Trendelenburg
OR
Supine with knee slightly flexed and externally rotated
This:
- Distends veins
- Improves visualization
For popliteal vein:
- Knee flexed
- Lateral decubitus/prone
Ultrasound Modes Used
|
Mode |
Role |
|
B-mode |
Anatomy + compression |
|
Color Doppler |
Flow assessment |
|
Spectral Doppler |
Venous waveform |
|
Augmentation maneuvers |
Detect obstruction |
Compression Ultrasound Technique
Apply probe pressure every:
- 1–2 cm above and below Points depending on 2 point or 3 point scan along vein course
2-Point Lower Extremity DVT Ultrasound: compression ultrasound including the femoral vein 1 to 2 cm above and below the saphenofemoral junction and the popliteal vein up to the calf veins confluence.
3-Point Lower Extremity DVT Ultrasound: compression ultrasound including the femoral vein 1 to 2 cm above and below the saphenofemoral junction, 1 to 2 cm above and below the bifurcation of the common femoral vein into the deep femoral vein and the (superficial) femoral vein, and lastly the popliteal vein up to the trifurcation into the anterior tibial vein, the posterior tibial vein, and the peroneal vein (Garcia 2018).
A normal vein:
- Completely disappears
A thrombosed vein:
- Partially compresses or not at all
How much pressure to apply-You should apply pressure until the pulsatile artery compresses slightly. If the adjacent vein compresses completely, there is no DVT
Acute vs Chronic DVT
|
Feature |
Acute |
Chronic |
|
Vein size |
Enlarged |
Small/fibrotic |
|
Thrombus |
Hypoechoic |
Hyperechoic |
|
Compressibility |
Poor |
Partial |
|
Collaterals |
Absent |
Present |
|
Wall thickening |
Minimal |
Marked |
|
Recanalization |
Absent |
Common |
Iliac Vein DVT
Difficult to visualize directly
Indirect signs:
- Loss of respiratory variation
- Continuous femoral waveform
- Extensive unilateral edema
Can use:
- Curvilinear probe
- Abdominal approach
Upper Extremity DVT POCUS
Common in:
- Central venous catheters
- PICC lines
- Malignancy
Evaluate:
- Internal jugular vein
- Subclavian vein
- Axillary vein
- Brachial veins
Challenge: Subclavian Vein
Cannot compress due to clavicle.
Diagnosis relies on:
- Doppler
- Color flow
- Loss of respiratory variation
Limitations of POCUS
False Negatives
Occur with:
- Calf DVT
- Nonocclusive clot
- Iliac thrombosis
- Obesity
- Severe edema
- Inexperienced operator
False Positives
- Chronic post-thrombotic changes
- Lymph nodes(disappear quickly if you attempt to trace it up and down)
- Baker cyst
- Hematoma
Mimics of DVT
|
Condition |
Ultrasound Finding |
|
Baker cyst |
Fluid collection(On Color Doppler, there should be no flow.) |
|
Cellulitis |
Cobblestoning |
|
Hematoma |
Mixed echogenicity |
|
Lymphedema |
Soft tissue edema |
|
Superficial thrombophlebitis |
Superficial clot |
Solution-identify that the vein is next to an artery. compare the vein in Short Axis(Circular ) and Long Axis views(Cylindrical)
Pregnancy and DVT Ultrasound
Pregnancy predisposes to:
- Left-sided DVT
- Iliac vein thrombosis
Challenges:
- Iliac compression by uterus
Indirect findings important.
Reporting DVT POCUS
Example:
“Noncompressible right popliteal vein with intraluminal echogenic thrombus consistent with acute proximal DVT.”
Special Situations
Phlegmasia Cerulea Dolens
Massive iliofemoral thrombosis causing:
- Severe edema
- Cyanosis
- Ischemia
POCUS:
- Extensive noncompressible proximal veins
Medical emergency.
May-Thurner Syndrome
Compression of:
- Left common iliac vein by right iliac artery
Suggest when:
- Recurrent left DVT
- Young female
- Iliac obstruction signs
REFERENCES
- https://www.pocus101.com/dvt-ultrasound-made-easy-step-by-step-guide/
- Varrias D, Palaiodimos L, Balasubramanian P, Barrera CA, Nauka P, Melainis AA, Zamora C, Zavras P, Napolitano M, Gulani P, Ntaios G, Faillace RT, Galen B. The Use of Point-of-Care Ultrasound (POCUS) in the Diagnosis of Deep Vein Thrombosis. J Clin Med. 2021 Aug 30;10(17):3903. doi: 10.3390/jcm10173903. PMID: 34501350; PMCID: PMC8432124.
