Pneumothorax
1. Definition
Pneumothorax is the presence of air in the pleural space, resulting in partial or complete lung collapse due to loss of negative intrapleural pressure.
In the ICU, pneumothorax is particularly important because it may occur due to:
- Mechanical ventilation
- Procedures (central line, thoracentesis)
- Trauma
- Underlying lung disease
The most dangerous form is tension pneumothorax, which causes obstructive shock and cardiac arrest if untreated.
2. Relevant Pleural Physiology
Normal Pleural Pressure
|
Phase |
Pleural Pressure |
|
End expiration |
−5 cm H₂O |
|
Inspiration |
−8 to −10 cm H₂O |
Negative pressure keeps the lung expanded against the chest wall.
When Pneumothorax Occurs
Air enters pleural space → pressure becomes less negative or positive → lung collapses.
Consequences:
- ↓ Lung compliance
- ↓ Vital capacity
- ↑ Shunt
- Hypoxemia
3. Classification of Pneumothorax
3.1 Based on Etiology
A. Spontaneous Pneumothorax
1. Primary Spontaneous Pneumothorax (PSP)
Occurs without known lung disease.
Risk factors:
- Tall thin males
- Smoking
- Apical blebs rupture
Typical age: 20–30 years
2. Secondary Spontaneous Pneumothorax (SSP)
Occurs in patients with underlying lung disease.
Common causes:
|
Disease |
Mechanism |
|
COPD |
Rupture of bullae |
|
Interstitial lung disease |
Fibrosis + cyst rupture |
|
Cystic fibrosis |
Bronchiectasis |
|
Tuberculosis |
Cavitary lesions |
|
Pneumocystis pneumonia |
Cyst rupture |
|
Lung cancer |
Necrosis |
SSP is more dangerous because patients already have poor lung reserve.
B. Traumatic Pneumothorax
Occurs due to injury to chest wall or lung.
Causes
Blunt trauma
- Rib fracture
- Pulmonary laceration
Penetrating trauma
- Stab injury
- Gunshot wound
C. Iatrogenic Pneumothorax
Very common in ICU.
Causes include:
|
Procedure |
Risk |
|
Central venous catheter |
Subclavian approach highest |
|
Thoracentesis |
Lung puncture |
|
Bronchoscopy |
Rare |
|
Mechanical ventilation |
Barotrauma |
|
Transbronchial biopsy |
Pneumothorax risk |
|
Percutaneous lung biopsy |
Common |
D. Barotrauma-Related Pneumothorax (ICU)
Occurs in:
- ARDS
- Mechanical ventilation
- High PEEP
- High tidal volume
- High plateau pressure
Mechanism:
Alveolar rupture → air dissects along bronchovascular sheath → pleural space.
4. Types of Pneumothorax
4.1 Simple Pneumothorax
Air enters pleural space but no progressive pressure build-up.
Features:
- Lung collapse
- No mediastinal shift
- Hemodynamics stable
4.2 Open Pneumothorax
Also called sucking chest wound.
Chest wall defect allows air to move freely between:
- pleural space
- atmosphere
Air enters through chest wall instead of trachea.
4.3 Tension Pneumothorax
Life-threatening emergency.
Mechanism:
One-way valve effect
Air enters pleural space during inspiration but cannot escape during expiration.
Consequences:
- Increasing intrathoracic pressure
- Lung collapse
- Mediastinal shift
- Compression of vena cava
- ↓ venous return
- Obstructive shock
Hemodynamic Effects
|
Effect |
Mechanism |
|
↓ Venous return |
IVC compression |
|
↓ Cardiac output |
Reduced preload |
|
Hypotension |
Shock |
|
Hypoxia |
Lung collapse |
|
Feature |
Simple Pneumothorax |
Tension Pneumothorax |
|
Blood pressure |
Normal |
Hypotension |
|
Trachea |
Central |
Deviated |
|
JVP |
Normal |
Elevated |
|
Respiratory distress |
Mild/moderate |
Severe |
|
Management |
Conservative/Drain |
Immediate decompression |
4.4. Pneumothorax Size Definition
According to British Thoracic Society:
|
Size |
Definition |
|
Small pneumothorax |
<2 cm rim between lung and chest wall |
|
Large pneumothorax |
≥2 cm rim |
Alternative method (ACCP):
Distance from apex to cupola >3 cm = large pneumothorax.
Pneumothorax Severity (British Thoracic Society)
|
Type |
Definition |
|
Small |
<2 cm rim |
|
Large |
≥2 cm |
5. Clinical Features
Symptoms
- Sudden chest pain
- Dyspnea
- Tachypnea
- Anxiety
Signs
|
Finding |
Mechanism |
|
Reduced breath sounds |
Collapsed lung |
|
Hyperresonant percussion |
Air |
|
Tracheal deviation |
Tension pneumothorax |
|
Tachycardia |
Hypoxia |
|
Hypotension |
Tension pneumothorax |
|
JVD |
Obstructive shock |
Classical Signs of Tension Pneumothorax
- Severe dyspnea
- Hypotension
- Distended neck veins
- Tracheal deviation
- Absent breath sounds
However in ICU these may be subtle or absent.
6. Pneumothorax in Mechanically Ventilated Patients
|
Sign |
Explanation |
|
Sudden hypoxia |
Shunt |
|
Sudden hypotension |
Tension |
|
Sudden ↑ peak airway pressure |
Reduced compliance |
|
Decreased tidal volume |
Air leak |
|
Ventilator alarm |
Compliance drop |
7. Diagnosis
Chest X-ray
Most common test.
Classic signs:
- Visible pleural line
- No lung markings peripheral to line
- Lung collapse
Signs on Supine X-ray (ICU)
Harder to detect.
Look for:
|
Sign |
Description |
|
Deep sulcus sign |
Abnormally deep costophrenic angle |
|
Hyperlucent hemithorax |
Increased air |
|
Sharp diaphragm |
Air outlining |
Lung Ultrasound (Preferred ICU Test)
Extremely sensitive.
Normal Lung US
Findings:
- Lung sliding
- B-lines
Pneumothorax Findings
|
Sign |
Meaning |
|
Absent lung sliding |
Air between pleura |
|
Absent B lines |
Air blocking ultrasound |
|
Lung point |
Diagnostic |
Lung Point
Transition between:
- normal lung sliding
- absent sliding
Highly specific for pneumothorax
M-mode Ultrasound Signs
|
Sign |
Appearance |
Interpretation |
|
Seashore sign |
Sand pattern below pleura |
Normal lung |
|
Barcode sign |
Parallel lines |
Pneumothorax |
CT Scan
Gold standard.
Indications:
- Uncertain diagnosis
- Trauma
- Small pneumothorax
8. Management Principles
Management depends on:
- Size
- Symptoms
- Stability
- Mechanical ventilation
Primary Spontaneous Pneumothorax
|
Condition |
Treatment |
|
Small + asymptomatic |
Observation + oxygen |
|
Small + symptomatic |
Needle aspiration |
|
Large pneumothorax |
Needle aspiration |
|
Aspiration failure |
Chest tube |
Secondary Spontaneous Pneumothorax
More aggressive treatment.
|
Condition |
Treatment |
|
Small (<1 cm) + stable |
Admit + oxygen |
|
1–2 cm |
Needle aspiration or small chest tube |
Oxygen Therapy
High-flow oxygen accelerates air absorption.
Mechanism:
Reduces nitrogen partial pressure in alveoli, increasing gradient for nitrogen absorption from pleural space.
Follow-up imaging:
- Chest X-ray after 6 hours
9. Emergency Management
If Tension Pneumothorax Suspected
DO NOT WAIT FOR X-RAY
Immediate needle decompression.
Needle Decompression
Sites
|
Site |
Landmark |
|
2nd intercostal space |
Midclavicular line |
|
5th intercostal space |
Anterior axillary line (preferred) |
Procedure
Large bore needle (14–16G).
Insert above rib → air release.
Temporary measure → chest tube required.
Problems with Needle Thoracostomy
Studies show failure rate up to 40–50% due to:
- Thick chest wall
- Short cannula
- Kinking
- Incorrect site
Hence many trauma guidelines prefer finger thoracostomy(5th ICS anterior axillary).
10. Chest Tube (Tube Thoracostomy)
Definitive management.
Site
Triangle of Safety
Boundaries:
- Anterior border of latissimus dorsi
- Lateral border of pectoralis major
- Line superior to nipple
- Apex below axilla
Tube Size
|
Situation |
Size |
|
Spontaneous pneumothorax |
16–22 Fr |
|
Trauma |
28–36 Fr |
|
ICU ventilated patients |
20–28 Fr |
Mechanism
Tube connected to:
- underwater seal
- suction
Allows continuous evacuation of air.
11. Ventilator Management
Important in ICU pneumothorax.
Strategies:
|
Strategy |
Reason |
|
Reduce tidal volume |
Prevent barotrauma |
|
Reduce PEEP |
Reduce pressure |
|
Limit plateau pressure |
<30 cm H₂O |
|
Permissive hypercapnia |
Lung protection |
12. Persistent Air Leak
Defined as air leak >5–7 days.
Causes:
- bronchopleural fistula
- lung necrosis
- ARDS
Management
Options:
|
Option |
Use |
|
Low pressure ventilation |
Reduce leak |
|
Endobronchial valve |
Selected cases |
|
Pleurodesis |
Recurrent |
|
Surgery |
Severe cases |
13. Complications
|
Complication |
Cause |
|
Recurrent pneumothorax |
Blebs |
|
Persistent air leak |
BPF |
|
Infection |
Tube insertion |
|
Hemothorax |
Vessel injury |
|
Re-expansion pulmonary edema |
Rapid drainage |
14. Re-Expansion Pulmonary Edema
Occurs after rapid re-expansion of collapsed lung.
Mechanism:
- capillary leak
- inflammatory injury
Risk factors:
- large pneumothorax
- 3 days duration
Prevention
Drain slowly.
15. Recurrence Prevention
Used in recurrent pneumothorax.
Options:
|
Method |
Mechanism |
|
Chemical pleurodesis |
Talc |
|
Surgical pleurodesis |
Thoracoscopy |
|
Blebs resection |
VATS |
16. Pneumothorax vs Hemothorax vs Pleural Effusion
|
Feature |
Pneumothorax |
Hemothorax |
Effusion |
|
Percussion |
Hyperresonant |
Dull |
Dull |
|
Breath sounds |
Decreased |
Decreased |
Decreased |
|
USG |
Absent sliding |
Fluid |
Fluid |
|
CXR |
Air |
Fluid level |
Fluid |
Guidelines mainly derived from:
- British Thoracic Society (BTS) 2023
- American College of Chest Physicians (ACCP)
