Pneumothorax

Pneumothorax 

1. Definition

Pneumothorax is the presence of air in the pleural space, resulting in partial or complete lung collapse due to loss of negative intrapleural pressure.

In the ICU, pneumothorax is particularly important because it may occur due to:

  • Mechanical ventilation
  • Procedures (central line, thoracentesis)
  • Trauma
  • Underlying lung disease

The most dangerous form is tension pneumothorax, which causes obstructive shock and cardiac arrest if untreated.


2. Relevant Pleural Physiology

Normal Pleural Pressure

Phase

Pleural Pressure

End expiration

−5 cm H₂O

Inspiration

−8 to −10 cm H₂O

Negative pressure keeps the lung expanded against the chest wall.


When Pneumothorax Occurs

Air enters pleural space pressure becomes less negative or positive lung collapses.

Consequences:

  • Lung compliance
  • Vital capacity
  • Shunt
  • Hypoxemia


3. Classification of Pneumothorax

3.1 Based on Etiology

A. Spontaneous Pneumothorax

1. Primary Spontaneous Pneumothorax (PSP)

Occurs without known lung disease.

Risk factors:

  • Tall thin males
  • Smoking
  • Apical blebs rupture

Typical age: 20–30 years


2. Secondary Spontaneous Pneumothorax (SSP)

Occurs in patients with underlying lung disease.

Common causes:

Disease

Mechanism

COPD

Rupture of bullae

Interstitial lung disease

Fibrosis + cyst rupture

Cystic fibrosis

Bronchiectasis

Tuberculosis

Cavitary lesions

Pneumocystis pneumonia

Cyst rupture

Lung cancer

Necrosis

SSP is more dangerous because patients already have poor lung reserve.


B. Traumatic Pneumothorax

Occurs due to injury to chest wall or lung.

Causes

Blunt trauma

  • Rib fracture
  • Pulmonary laceration

Penetrating trauma

  • Stab injury
  • Gunshot wound


C. Iatrogenic Pneumothorax

Very common in ICU.

Causes include:

Procedure

Risk

Central venous catheter

Subclavian approach highest

Thoracentesis

Lung puncture

Bronchoscopy

Rare

Mechanical ventilation

Barotrauma

Transbronchial biopsy

Pneumothorax risk

Percutaneous lung biopsy

Common


D. Barotrauma-Related Pneumothorax (ICU)

Occurs in:

  • ARDS
  • Mechanical ventilation
  • High PEEP
  • High tidal volume
  • High plateau pressure

Mechanism:

Alveolar rupture air dissects along bronchovascular sheath pleural space.


4. Types of Pneumothorax

4.1 Simple Pneumothorax

Air enters pleural space but no progressive pressure build-up.

Features:

  • Lung collapse
  • No mediastinal shift
  • Hemodynamics stable


4.2 Open Pneumothorax

Also called sucking chest wound.

Chest wall defect allows air to move freely between:

  • pleural space
  • atmosphere

Air enters through chest wall instead of trachea.


4.3 Tension Pneumothorax 

Life-threatening emergency.

Mechanism:

One-way valve effect

Air enters pleural space during inspiration but cannot escape during expiration.

Consequences:

  • Increasing intrathoracic pressure
  • Lung collapse
  • Mediastinal shift
  • Compression of vena cava
  • venous return
  • Obstructive shock


Hemodynamic Effects

Effect

Mechanism

Venous return

IVC compression

Cardiac output

Reduced preload

Hypotension

Shock

Hypoxia

Lung collapse


Feature

Simple Pneumothorax

Tension Pneumothorax

Blood pressure

Normal

Hypotension

Trachea

Central

Deviated

JVP

Normal

Elevated

Respiratory distress

Mild/moderate

Severe

Management

Conservative/Drain

Immediate decompression


4.4. Pneumothorax Size Definition

According to British Thoracic Society:

Size

Definition

Small pneumothorax

<2 cm rim between lung and chest wall

Large pneumothorax

≥2 cm rim

Alternative method (ACCP):

Distance from apex to cupola >3 cm = large pneumothorax.


 Pneumothorax Severity (British Thoracic Society)

Type

Definition

Small

<2 cm rim

Large

≥2 cm


5. Clinical Features

Symptoms

  • Sudden chest pain
  • Dyspnea
  • Tachypnea
  • Anxiety


Signs

Finding

Mechanism

Reduced breath sounds

Collapsed lung

Hyperresonant percussion

Air

Tracheal deviation

Tension pneumothorax

Tachycardia

Hypoxia

Hypotension

Tension pneumothorax

JVD

Obstructive shock


Classical Signs of Tension Pneumothorax

  • Severe dyspnea
  • Hypotension
  • Distended neck veins
  • Tracheal deviation
  • Absent breath sounds

However in ICU these may be subtle or absent.


6. Pneumothorax in Mechanically Ventilated Patients

Sign

Explanation

Sudden hypoxia

Shunt

Sudden hypotension

Tension

Sudden peak airway pressure

Reduced compliance

Decreased tidal volume

Air leak

Ventilator alarm

Compliance drop



7. Diagnosis

 Chest X-ray

Most common test.

Classic signs:

  • Visible pleural line
  • No lung markings peripheral to line
  • Lung collapse


Signs on Supine X-ray (ICU)

Harder to detect.

Look for:

Sign

Description

Deep sulcus sign

Abnormally deep costophrenic angle

Hyperlucent hemithorax

Increased air

Sharp diaphragm

Air outlining


 Lung Ultrasound (Preferred ICU Test)

Extremely sensitive.

Normal Lung US

Findings:

  • Lung sliding
  • B-lines


Pneumothorax Findings

Sign

Meaning

Absent lung sliding

Air between pleura

Absent B lines

Air blocking ultrasound

Lung point

Diagnostic


Lung Point

Transition between:

  • normal lung sliding
  • absent sliding

Highly specific for pneumothorax

M-mode Ultrasound Signs

Sign

Appearance

Interpretation

Seashore sign

Sand pattern below pleura

Normal lung

Barcode sign

Parallel lines

Pneumothorax


 CT Scan

Gold standard.

Indications:

  • Uncertain diagnosis
  • Trauma
  • Small pneumothorax


8. Management Principles

Management depends on:

  • Size
  • Symptoms
  • Stability
  • Mechanical ventilation

Primary Spontaneous Pneumothorax

Condition

Treatment

Small + asymptomatic

Observation + oxygen

Small + symptomatic

Needle aspiration

Large pneumothorax

Needle aspiration

Aspiration failure

Chest tube


Secondary Spontaneous Pneumothorax

More aggressive treatment.

Condition

Treatment

Small (<1 cm) + stable

Admit + oxygen

1–2 cm

Needle aspiration or small chest tube


Oxygen Therapy

High-flow oxygen accelerates air absorption.

Mechanism:

Reduces nitrogen partial pressure in alveoli, increasing gradient for nitrogen absorption from pleural space.


Follow-up imaging:

  • Chest X-ray after 6 hours


9.  Emergency Management

If Tension Pneumothorax Suspected

DO NOT WAIT FOR X-RAY

Immediate needle decompression.


Needle Decompression

Sites

Site

Landmark

2nd intercostal space

Midclavicular line

5th intercostal space

Anterior axillary line (preferred)


Procedure

Large bore needle (14–16G).

Insert above rib air release.

Temporary measure chest tube required.

Problems with Needle Thoracostomy

Studies show failure rate up to 40–50% due to:

  • Thick chest wall
  • Short cannula
  • Kinking
  • Incorrect site

Hence many trauma guidelines prefer finger thoracostomy(5th ICS anterior axillary).


10. Chest Tube (Tube Thoracostomy)

Definitive management.

Site

Triangle of Safety

Boundaries:

  • Anterior border of latissimus dorsi
  • Lateral border of pectoralis major
  • Line superior to nipple
  • Apex below axilla


Tube Size

Situation

Size

Spontaneous pneumothorax

16–22 Fr

Trauma

28–36 Fr

ICU ventilated patients

20–28 Fr


Mechanism

Tube connected to:

  • underwater seal
  • suction

Allows continuous evacuation of air.


11. Ventilator Management

Important in ICU pneumothorax.

Strategies:

Strategy

Reason

Reduce tidal volume

Prevent barotrauma

Reduce PEEP

Reduce pressure

Limit plateau pressure

<30 cm H₂O

Permissive hypercapnia

Lung protection


12. Persistent Air Leak

Defined as air leak >5–7 days.

Causes:

  • bronchopleural fistula
  • lung necrosis
  • ARDS


Management

Options:

Option

Use

Low pressure ventilation

Reduce leak

Endobronchial valve

Selected cases

Pleurodesis

Recurrent

Surgery

Severe cases



13. Complications

Complication

Cause

Recurrent pneumothorax

Blebs

Persistent air leak

BPF

Infection

Tube insertion

Hemothorax

Vessel injury

Re-expansion pulmonary edema

Rapid drainage


14. Re-Expansion Pulmonary Edema

Occurs after rapid re-expansion of collapsed lung.

Mechanism:

  • capillary leak
  • inflammatory injury

Risk factors:

  • large pneumothorax
  • 3 days duration


Prevention

Drain slowly.


15. Recurrence Prevention

Used in recurrent pneumothorax.

Options:

Method

Mechanism

Chemical pleurodesis

Talc

Surgical pleurodesis

Thoracoscopy

Blebs resection

VATS



16. Pneumothorax vs Hemothorax vs Pleural Effusion

Feature

Pneumothorax

Hemothorax

Effusion

Percussion

Hyperresonant

Dull

Dull

Breath sounds

Decreased

Decreased

Decreased

USG

Absent sliding

Fluid

Fluid

CXR

Air

Fluid level

Fluid


Guidelines mainly derived from:

  • British Thoracic Society (BTS) 2023
  • American College of Chest Physicians (ACCP)

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