REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta)
1. Definition
REBOA = temporary endovascular aortic occlusion using an inflatable balloon inserted via the femoral artery to control non-compressible torso hemorrhage (NCTH).
It provides:
- Proximal control of bleeding
- Augmentation of coronary and cerebral perfusion
- Bridge to definitive hemorrhage control (OR / IR / damage control surgery)
It is a less invasive alternative to resuscitative thoracotomy with aortic cross-clamping.
2. Historical Perspective
- First described in the 1950s (Korean war)
- Modern resurgence with low-profile catheters (~7 Fr)
- Now incorporated in trauma algorithms (EAST, WSES, ACS TQIP, ELSO in select ECMO contexts)
3. Physiological Basis
Aortic Occlusion Causes:
↑ Proximal MAP
- Improves coronary perfusion pressure
- Improves cerebral perfusion
↓ Distal Flow
- Reduces hemorrhage distal to balloon
- Produces ischemia below occlusion
Hemodynamic Effects:
|
Parameter |
Effect |
|
MAP |
↑ 30–50 mmHg |
|
Afterload |
↑ markedly |
|
Cardiac workload |
↑ |
|
Distal ischemia |
Progressive |
|
Lactate |
Rises rapidly |
4. Aortic Zones
|
Zone |
Location |
Indication |
|
Zone 1 |
Left subclavian → celiac trunk |
Intra-abdominal hemorrhage |
|
Zone 2 |
Celiac → renal arteries |
Avoid (no placement) |
|
Zone 3 |
Renal arteries → aortic bifurcation |
Pelvic hemorrhage |
🔴 Zone 1
- For severe abdominal bleeding
- Maximum ischemic burden
🟢 Zone 3
- For pelvic fracture bleeding
- Lower ischemic risk
Zone 2 = No man’s land
5. Indications
Primary Indication:
Hemorrhagic shock due to non-compressible torso hemorrhage
Trauma:
- Blunt abdominal trauma
- Pelvic fracture with massive hemorrhage
- Junctional bleeding not controllable
Non-Trauma (Selective):
- Ruptured abdominal aortic aneurysm
- Massive GI bleed (bridge)
- Postpartum hemorrhage (rare but described)
Hemodynamic Criteria:
- SBP < 90 mmHg despite resuscitation
- Transient responder
- Cardiac arrest from hemorrhage (before thoracotomy)
6. Contraindications
Absolute:
- Thoracic bleeding proximal to occlusion
- Unsalvageable injury
- Aortic injury proximal to balloon
Relative:
- Severe traumatic brain injury (afterload increase risk)
- Prolonged CPR (>10–15 min no ROSC)
- Aortic dissection
7. Procedure Steps
Step 1: Femoral Artery Access
- Ultrasound-guided
- Prefer common femoral artery (above bifurcation)
- 7 Fr sheath (modern systems)
Step 2: Catheter Advancement
- External landmark-based measurement OR fluoroscopy
- Zone 1: ~45 cm
- Zone 3: ~25 cm
Step 3: Balloon Inflation
- Inflate with saline + contrast
- Monitor MAP response
- Confirm by:
- Loss of femoral pulse
- Radiography if available
Step 4: Secure & Prepare for Definitive Control
8. Occlusion Strategies
1. Complete Occlusion
- Full balloon inflation
- Maximum hemodynamic support
- High ischemia risk
2. Partial REBOA (pREBOA)
- Controlled partial inflation
- Allows minimal distal perfusion
- Reduces ischemia-reperfusion injury
- Current preferred strategy
3. Intermittent REBOA
- Deflate periodically
- Used when prolonged occlusion unavoidable
9️⃣ Time Limits
|
Zone |
Safe Occlusion Time |
|
Zone 1 |
Ideally < 30–45 min |
|
Zone 3 |
Up to 60 min (relative) |
After 60 min:
- Severe metabolic acidosis
- Reperfusion injury
- Multiorgan failure
10. Complications
1️⃣ Ischemic Complications
- Limb ischemia
- Bowel ischemia
- Renal failure
- Spinal cord ischemia
2️⃣ Reperfusion Injury
- Massive acidosis
- Hyperkalemia
- Hypotension on deflation
- Ventricular arrhythmias
3️⃣ Vascular Injury
- Femoral artery thrombosis
- Dissection
- Pseudoaneurysm
4️⃣ Balloon Rupture
5️⃣ Compartment Syndrome
11. REBOA vs Resuscitative Thoracotomy
|
Feature |
REBOA |
Thoracotomy |
|
Invasiveness |
Percutaneous |
Open chest |
|
Aortic control |
Endovascular |
Cross-clamp |
|
Training required |
High |
Very high |
|
Use in ED |
Yes |
Yes |
|
Survival (blunt trauma) |
Better in select patients |
Poor |
Thoracotomy preferred in:
- Penetrating cardiac injury
- Cardiac tamponade
12. REBOA in Cardiac Arrest
- Used in traumatic cardiac arrest from hemorrhage
- Can restore coronary perfusion
- If no ROSC within short time → poor outcome
Not indicated in:
- Medical cardiac arrest
- Non-hemorrhagic arrest
13. REBOA in Pelvic Fracture
Zone 3 preferred
- Reduces pelvic arterial bleeding
- Bridge to:
- Angioembolization
- Pelvic packing
- External fixation
14. Metabolic Consequences After Deflation
Sudden deflation causes:
- ↓ SVR
- ↓ MAP
- Acidosis washout
- Hyperkalemia
- Myocardial depression
Management During Deflation:
- Gradual deflation
- Calcium
- Bicarbonate (selective)
- Vasopressors ready
- Massive transfusion ongoing
15. Evidence & Outcomes
- Improves short-term hemodynamics
- Survival benefit unclear in all-comers
- Best benefit in:
- Severe pelvic hemorrhage
- Transient responders
Poor outcomes in:
- Prolonged occlusion
- Delayed definitive control
- Severe TBI
16. Integration in Trauma Algorithm
REBOA sits between:
Massive transfusion protocol
⬇
Persistent hypotension
⬇
REBOA (if NCTH suspected)
⬇
Damage control surgery / IR
17. Monitoring in ICU After REBOA
- Serial lactate
- ABG every 30–60 min
- Limb perfusion checks hourly
- Doppler pulses
- CK levels
- Renal function
- Compartment pressure if needed
