REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta)

1. Definition

REBOA = temporary endovascular aortic occlusion using an inflatable balloon inserted via the femoral artery to control non-compressible torso hemorrhage (NCTH).

It provides:

  • Proximal control of bleeding
  • Augmentation of coronary and cerebral perfusion
  • Bridge to definitive hemorrhage control (OR / IR / damage control surgery)

It is a less invasive alternative to resuscitative thoracotomy with aortic cross-clamping.


2. Historical Perspective

  • First described in the 1950s (Korean war)
  • Modern resurgence with low-profile catheters (~7 Fr)
  • Now incorporated in trauma algorithms (EAST, WSES, ACS TQIP, ELSO in select ECMO contexts)


3. Physiological Basis 

Aortic Occlusion Causes:

Proximal MAP

  • Improves coronary perfusion pressure
  • Improves cerebral perfusion

Distal Flow

  • Reduces hemorrhage distal to balloon
  • Produces ischemia below occlusion

Hemodynamic Effects:

Parameter

Effect

MAP

30–50 mmHg

Afterload

markedly

Cardiac workload

Distal ischemia

Progressive

Lactate

Rises rapidly


4. Aortic Zones 

Zone

Location

Indication

Zone 1

Left subclavian celiac trunk

Intra-abdominal hemorrhage

Zone 2

Celiac renal arteries

Avoid (no placement)

Zone 3

Renal arteries aortic bifurcation

Pelvic hemorrhage

🔴 Zone 1

  • For severe abdominal bleeding
  • Maximum ischemic burden

🟢 Zone 3

  • For pelvic fracture bleeding
  • Lower ischemic risk

Zone 2 = No man’s land


5. Indications 

Primary Indication:

Hemorrhagic shock due to non-compressible torso hemorrhage

Trauma:

  • Blunt abdominal trauma
  • Pelvic fracture with massive hemorrhage
  • Junctional bleeding not controllable

Non-Trauma (Selective):

  • Ruptured abdominal aortic aneurysm
  • Massive GI bleed (bridge)
  • Postpartum hemorrhage (rare but described)

Hemodynamic Criteria:

  • SBP < 90 mmHg despite resuscitation
  • Transient responder
  • Cardiac arrest from hemorrhage (before thoracotomy)


6. Contraindications

Absolute:

  • Thoracic bleeding proximal to occlusion
  • Unsalvageable injury
  • Aortic injury proximal to balloon

Relative:

  • Severe traumatic brain injury (afterload increase risk)
  • Prolonged CPR (>10–15 min no ROSC)
  • Aortic dissection


7. Procedure Steps 

Step 1: Femoral Artery Access

  • Ultrasound-guided
  • Prefer common femoral artery (above bifurcation)
  • 7 Fr sheath (modern systems)

Step 2: Catheter Advancement

  • External landmark-based measurement OR fluoroscopy
  • Zone 1: ~45 cm
  • Zone 3: ~25 cm

Step 3: Balloon Inflation

  • Inflate with saline + contrast
  • Monitor MAP response
  • Confirm by:
    • Loss of femoral pulse
    • Radiography if available

Step 4: Secure & Prepare for Definitive Control


8. Occlusion Strategies 

1. Complete Occlusion

  • Full balloon inflation
  • Maximum hemodynamic support
  • High ischemia risk

2. Partial REBOA (pREBOA)

  • Controlled partial inflation
  • Allows minimal distal perfusion
  • Reduces ischemia-reperfusion injury
  • Current preferred strategy

3. Intermittent REBOA

  • Deflate periodically
  • Used when prolonged occlusion unavoidable


9️⃣ Time Limits 

Zone

Safe Occlusion Time

Zone 1

Ideally < 30–45 min

Zone 3

Up to 60 min (relative)

After 60 min:

  • Severe metabolic acidosis
  • Reperfusion injury
  • Multiorgan failure


10. Complications 

1️⃣ Ischemic Complications

  • Limb ischemia
  • Bowel ischemia
  • Renal failure
  • Spinal cord ischemia

2️⃣ Reperfusion Injury

  • Massive acidosis
  • Hyperkalemia
  • Hypotension on deflation
  • Ventricular arrhythmias

3️⃣ Vascular Injury

  • Femoral artery thrombosis
  • Dissection
  • Pseudoaneurysm

4️⃣ Balloon Rupture

5️⃣ Compartment Syndrome


11. REBOA vs Resuscitative Thoracotomy

Feature

REBOA

Thoracotomy

Invasiveness

Percutaneous

Open chest

Aortic control

Endovascular

Cross-clamp

Training required

High

Very high

Use in ED

Yes

Yes

Survival (blunt trauma)

Better in select patients

Poor

Thoracotomy preferred in:

  • Penetrating cardiac injury
  • Cardiac tamponade


12. REBOA in Cardiac Arrest

  • Used in traumatic cardiac arrest from hemorrhage
  • Can restore coronary perfusion
  • If no ROSC within short time poor outcome

Not indicated in:

  • Medical cardiac arrest
  • Non-hemorrhagic arrest


13. REBOA in Pelvic Fracture

Zone 3 preferred

  • Reduces pelvic arterial bleeding
  • Bridge to:
    • Angioembolization
    • Pelvic packing
    • External fixation


14. Metabolic Consequences After Deflation 

Sudden deflation causes:

  • SVR
  • MAP
  • Acidosis washout
  • Hyperkalemia
  • Myocardial depression

Management During Deflation:

  • Gradual deflation
  • Calcium
  • Bicarbonate (selective)
  • Vasopressors ready
  • Massive transfusion ongoing


15. Evidence & Outcomes 

  • Improves short-term hemodynamics
  • Survival benefit unclear in all-comers
  • Best benefit in:
    • Severe pelvic hemorrhage
    • Transient responders

Poor outcomes in:

  • Prolonged occlusion
  • Delayed definitive control
  • Severe TBI


16. Integration in Trauma Algorithm

REBOA sits between:

Massive transfusion protocol

Persistent hypotension

REBOA (if NCTH suspected)

Damage control surgery / IR


17. Monitoring in ICU After REBOA

  • Serial lactate
  • ABG every 30–60 min
  • Limb perfusion checks hourly
  • Doppler pulses
  • CK levels
  • Renal function
  • Compartment pressure if needed