Nasal Prongs (Nasal Cannula) 

1. Definition

Nasal prongs (nasal cannula) are a low-flow oxygen delivery device Key characteristics:

  • Low-flow oxygen device
  • Delivers oxygen through nasal route
  • Allows patient to talk, eat, and drink
  • Provides variable FiO₂ depending on patient ventilation


2. Principle of Oxygen Delivery

Nasal prongs deliver oxygen by entraining room air during inspiration.

The actual FiO₂ depends on:

  • Oxygen flow rate
  • Patient tidal volume
  • Respiratory rate
  • Inspiratory flow
  • Mouth breathing

Because room air mixes with oxygen, FiO₂ is variable and unpredictable.


3. Oxygen Flow Rate and FiO₂

Classical ICU Rule (4% Rule)

Each 1 L/min increases FiO₂ by ~4% above room air.

Oxygen Flow

Approximate FiO₂

Room air

21%

1 L/min

24%

2 L/min

28%

3 L/min

32%

4 L/min

36%

5 L/min

40%

6 L/min

44%


4. Maximum Recommended Flow

Standard nasal cannula:

Parameter

Value

Minimum flow

1 L/min

Typical range

1–4 L/min

Maximum flow

6 L/min

Higher flows cause:

  • Nasal dryness
  • Epistaxis
  • Mucosal irritation


5. Anatomical Oxygen Reservoir Effect

The nasopharynx acts as a small oxygen reservoir.

During expiration:

  • Oxygen accumulates in nasopharynx

During next inspiration:

  • Stored oxygen is inhaled first

This increases effective oxygen delivery efficiency.


6. Contraindications

Absolute contraindications are rare but include:

Contraindication

Reason

Severe respiratory distress

Insufficient FiO₂

Nasal obstruction

Oxygen cannot enter

Facial trauma

Cannula cannot be placed

Severe hypoxemia

Requires higher FiO₂ device

Apnea

No spontaneous breathing


7. Advantages

Advantage

Explanation

Comfortable

Least intrusive oxygen device

Allows speech

Patient can talk normally

Allows eating

No mask obstruction

Easy to apply

Minimal training required

Cheap

Low cost device

Mobility

Patient can ambulate


8. Disadvantages

Disadvantage

Explanation

Variable FiO₂

Depends on breathing pattern

Limited FiO₂

Maximum ~44%

Nasal dryness

Especially without humidification

Epistaxis

With high flows

Mouth breathing reduces efficacy

Oxygen bypassed



9. Humidification

Humidification is usually not required at low flow.

Recommended when:

Flow rate

Recommendation

≤4 L/min

Usually not needed

>4 L/min

Humidification preferred

Long-term oxygen therapy

Recommended

Humidification prevents:

  • Mucosal drying
  • Thick secretions
  • Epistaxis


10. Comparison with Other Oxygen Devices

Device

FiO₂

Flow

Type

Nasal cannula

24–44%

1–6 L/min

Low flow

Simple face mask

35–60%

5–10 L/min

Low flow

Venturi mask

24–60%

Variable

High precision

Non-rebreather mask

60–95%

10–15 L/min

High FiO₂

HFNC

Up to 100%

30–70 L/min

High flow


Feature

Standard Cannula

HFNC

Flow

≤6 L/min

30–70 L/min

FiO₂

≤44%

Up to 100%

Humidification

Optional

Heated humidified

Positive pressure

No

Mild PEEP effect

Dead space washout

Minimal

Significant




2. Target saturation (Guidelines)

Patient group

Target SpO₂

Most ICU patients

92–96%

COPD/CO₂ retainers

88–92%

Post cardiac arrest

94–98%

(WHO / BTS / ERS guidelines)